Mouse Sirt3 (NAD-dependent deacetylase sirtuin-3) ELISA Kit

Product specifications

ELISA Kits

Mouse

Colorimetric

4 hours

Sandwich ELISA, Double Antibody

0.313-20ng/ml

0.188ng/ml

96T

ELISA

Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples

Shipped within 10-14 working days.

2-8 °C for 12 months

Q8R104

SIR2L3,NAD-dependent protein deacetylase sirtuin-3 mitochondrial,SIR2-like protein 3,SIR2L3,hSIRT3

Elisa kits for Sirt3

RUO

SIRT3 is a NAD+-dependent deacetylase primarily localized in the mitochondria, where it plays a critical role in regulating mitochondrial metabolism, energy production, and oxidative stress response SIRT3 deacetylates and activates key mitochondrial enzymes, including acetyl-CoA synthetase 2 (ACSS2), superoxide dismutase 2 (SOD2), and components of the electron transport chain, enhancing ATP production, fatty acid oxidation, and antioxidant defense SIRT3 is essential for maintaining mitochondrial homeostasis during energy stress, such as fasting or caloric restriction, by stimulating pathways that improve energy efficiency and reduce reactive oxygen species (ROS) levels SIRT3 also promotes cellular survival under oxidative stress by deacetylating SOD2, which neutralizes superoxide radicals Dysregulation of SIRT3 is associated with aging, metabolic disorders, cardiovascular disease, and neurodegeneration, where impaired mitochondrial function leads to cellular damage and energy deficiency SIRT3 has tumor suppressor properties as it inhibits aerobic glycolysis (Warburg effect) in cancer cells by regulating key metabolic enzymes Its activation is being explored as a therapeutic strategy to combat mitochondrial dysfunction, improve metabolic health, and delay aging-related diseases

Related Products

Rat Sirtuin 3 (SIRT3) Protein

Rat Sirtuin 3 (SIRT3) Protein is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).

Ver Producto

Human Sirtuin 3 (SIRT3) ELISA Kit

Human Sirtuin 3 (SIRT3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Sirtuin 3 concentrations in tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Sirtuin 3 (SIRT3)

Ver Producto

Human Sirtuin 3 (SIRT3) CLIA Kit

Human Sirtuin 3 (SIRT3) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.

Ver Producto