Mouse SAM and SH3 domain-containing protein 3 (SASH3) ELISA Kit

Product specifications

ELISA Kits

SAM and SH3 domain-containing protein 3 (SASH3)

Mouse

Colorimetric

Quantitative

Sandwich

0.156 ng/ml - 10 ng/ml

< 0.094 ng/ml

Optimal dilutions/concentrations should be determined by the end user.

96 tests

Lyophilized

ELISA

Serum, plasma and other biological fluids.

Shipped within 5-12 working days. The validity for this kit is 6 months.

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

No

Q8K352

74131

753P9,CXorf9,HACS2, MD102,SH3D6C,SLY,SH3 protein expressed in lymphocytes homolog

Elisa kits for SASH3

RUO

Validity: The validity for this kit is 6 months.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

SAM and SH3 domain containing 3 (SASH3), also known as the signaling lymphocyte activation molecule (SLAM)-associated protein-like molecule, is an adaptor protein predominantly expressed in immune cells, including T cells and B cells SASH3 plays a critical role in T-cell receptor (TCR) and B-cell receptor (BCR) signaling, where it facilitates downstream pathways essential for lymphocyte activation, differentiation, and survival Through its SH3 and SAM domains, SASH3 interacts with other signaling proteins and regulates immune responses, including cytokine production and antigen recognition Dysregulation or mutations in SASH3 are linked to immune deficiencies and autoimmune diseases, as impaired signaling affects lymphocyte function and immune tolerance SASH3 is also implicated in hematopoietic malignancies, where its altered expression contributes to abnormal immune cell proliferation and survival Recent studies indicate its role in regulating inflammation and adaptive immunity, highlighting its importance in maintaining immune system balance Its involvement in critical signaling pathways positions SASH3 as a key regulator of immune function and a potential target for therapeutic intervention in immunological disorders and cancers

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