Mouse Relaxin/Insulin Like Family Peptide Receptor 2 (RXFP2) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Relaxin/Insulin Like Family Peptide Receptor 2 (RXFP2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx390435
tested applications
ELISA
Description
Mouse Relaxin/Insulin Like Family Peptide Receptor 2 (RXFP2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse RXFP2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Relaxin/Insulin Like Family Peptide Receptor 2 (RXFP2) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.094 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q91ZZ5 |
| Gene ID | 140498 |
| Alias | RXFP2,GPR106,RXFPR2,relaxin receptor 2,LGR8,INSL3 receptor,leucine-rich repeat-containing G protein-coupled receptor 8,relaxin/insulin like family peptide receptor 2,GREAT, INSL3R, LGR8, LGR8.1 |
| Background | Elisa kits for RXFP2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
RXFP2 is another member of the relaxin/insulin-like family peptide receptors, activated by relaxin-2 and its analogs. RXFP2 primarily couples to Gs proteins, stimulating adenylate cyclase to increase cAMP levels and induce downstream effects such as smooth muscle relaxation, vasodilation, and remodeling of tissues. RXFP2 is expressed in various tissues, including the brain, reproductive system, and heart, where it is involved in regulating reproductive functions such as ovulation, pregnancy, and labor, as well as maintaining vascular tone. RXFP2 also plays a key role in modulating heart function by influencing cardiac remodeling, fibrosis, and endothelial function. Dysregulation of RXFP2 signaling has been implicated in cardiovascular diseases, infertility, and pregnancy complications. Targeting RXFP2 with agonists or antagonists holds promise for treating conditions such as heart failure, preterm labor, and fibrotic diseases by promoting tissue remodeling and vascular homeostasis.
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