Mouse Relaxin/Insulin Like Family Peptide Receptor 1 (RXFP1) ELISA Kit
546€ (96 tests)
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935106861
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name
Mouse Relaxin/Insulin Like Family Peptide Receptor 1 (RXFP1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx254542
tested applications
ELISA
Description
Mouse Relaxin/Insulin Like Family Peptide Receptor 1 (RXFP1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse RXFP1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Relaxin/Insulin Like Family Peptide Receptor 1 (RXFP1) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 15.6 pg/ml - 1000 pg/ml |
| Sensitivity | 9.38 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q6R6I7 |
| Gene ID | 381489 |
| NCBI Accession | NP_997617.1 |
| Alias | RXFP1,LGR7,RXFPR1,relaxin receptor 1,leucine-rich repeat-containing G-protein-coupled receptor 7,RX1,relaxin/insulin like family peptide receptor 1 |
| Background | Elisa kits for RXFP1 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
RXFP1 is a G protein-coupled receptor activated by relaxin, a peptide hormone involved in reproductive, cardiovascular, and renal physiology. RXFP1 primarily couples to Gs proteins, stimulating adenylate cyclase and increasing intracellular cAMP levels, which in turn affects smooth muscle relaxation, vasodilation, and cell proliferation. RXFP1 is expressed in the reproductive tissues, kidneys, and blood vessels, where it plays a role in pregnancy, cardiac remodeling, and kidney function. During pregnancy, RXFP1 helps modulate uterine relaxation and cervical ripening. In cardiovascular health, RXFP1 is involved in regulating blood pressure and maintaining vascular integrity. Dysregulation of RXFP1 is linked to pregnancy complications, hypertension, and fibrosis. As a target for cardiovascular and renal diseases, RXFP1 receptor agonists are being explored for their potential in promoting tissue repair and reducing fibrosis, while antagonists could be used to modulate pregnancy-related vascular changes.
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