Mouse Relaxin/Insulin Like Family Peptide Receptor 1 (RXFP1) ELISA Kit

Este producto es parte de LGR - Leucine Rich Repeat Containing G Protein-Coupled Receptor
Mouse Relaxin/Insulin Like Family Peptide Receptor 1 (RXFP1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

546€ (96 tests)

Elisa kits for RXFP1

proveedor

Abbexa

reference

abx254542

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Relaxin/Insulin Like Family Peptide Receptor 1 (RXFP1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse RXFP1 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

RXFP1 is a G protein-coupled receptor activated by relaxin, a peptide hormone involved in reproductive, cardiovascular, and renal physiology. RXFP1 primarily couples to Gs proteins, stimulating adenylate cyclase and increasing intracellular cAMP levels, which in turn affects smooth muscle relaxation, vasodilation, and cell proliferation. RXFP1 is expressed in the reproductive tissues, kidneys, and blood vessels, where it plays a role in pregnancy, cardiac remodeling, and kidney function. During pregnancy, RXFP1 helps modulate uterine relaxation and cervical ripening. In cardiovascular health, RXFP1 is involved in regulating blood pressure and maintaining vascular integrity. Dysregulation of RXFP1 is linked to pregnancy complications, hypertension, and fibrosis. As a target for cardiovascular and renal diseases, RXFP1 receptor agonists are being explored for their potential in promoting tissue repair and reducing fibrosis, while antagonists could be used to modulate pregnancy-related vascular changes.

Características del producto

category

ELISA Kits


immunogen target

Relaxin/Insulin Like Family Peptide Receptor 1 (RXFP1)


reactivity

Mouse


test range

15.6 pg/ml - 1000 pg/ml


sensitivity

9.38 pg/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

RXFP1,LGR7,RXFPR1,relaxin receptor 1,leucine-rich repeat-containing G-protein-coupled receptor 7,RX1,relaxin/insulin like family peptide receptor 1


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

RXFP1


dry ice

No


NCBI accession

NP_997617.1


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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