Mouse Relaxin-3 receptor 2 (RXFP4) ELISA Kit

715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Relaxin-3 receptor 2 (RXFP4) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx542656
tested applications
ELISA
Description
Mouse Relaxin-3 receptor 2 (RXFP4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Relaxin-3 receptor 2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Relaxin-3 receptor 2 (RXFP4) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q7TQP4 |
| Gene ID | 242093 |
| Alias | RXFP4,RLN3R2,GPCR142,INSL5 receptor,RXFPR4,G protein-coupled receptor 100,relaxin/insulin-like family peptide receptor 4,relaxin/insulin like family peptide receptor 4,GPR100 |
| Background | Elisa Kits for: RXFP4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
RXFP4, also known as the INSL5 receptor, is a G protein-coupled receptor activated by insulin-like peptide 5 (INSL5), a peptide hormone that plays a role in regulating gastrointestinal function, reproductive physiology, and metabolism. RXFP4 primarily couples to Gs proteins, increasing cAMP levels, and activating pathways involved in smooth muscle relaxation and hormone secretion. It is expressed in the gastrointestinal tract, pancreas, and reproductive organs, where it regulates processes such as intestinal motility, glucose homeostasis, and reproductive function. INSL5 and RXFP4 signaling is involved in the regulation of feeding behavior and insulin secretion. Dysregulation of RXFP4 signaling has been linked to metabolic disorders, such as obesity and type 2 diabetes, and gastrointestinal conditions, including irritable bowel syndrome (IBS). RXFP4 antagonists and agonists are being investigated for their potential therapeutic applications in treating metabolic diseases and gastrointestinal disorders.
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