Mouse Receptor-type tyrosine-protein phosphatase mu (PTPRM) ELISA Kit

Este producto es parte de PTPR - protein tyrosine phosphatase receptor type
Mouse Receptor-type tyrosine-protein phosphatase mu (PTPRM) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

687.5€ (96 tests)

Elisa Kits PTPRM

proveedor

Abbexa

reference

abx540756

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Receptor-type tyrosine-protein phosphatase mu (PTPRM) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Receptor-type tyrosine-protein phosphatase mu concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

PTPRM, also known as RPTPμ, is a receptor-like protein tyrosine phosphatase that regulates cell-cell adhesion, signaling, and growth suppression. Structurally, PTPRM contains extracellular Ig-like and fibronectin type III domains, a transmembrane domain, and two intracellular phosphatase domains. PTPRM mediates homophilic binding, meaning it interacts with other PTPRM molecules on adjacent cells to facilitate cell-cell adhesion. It plays essential roles in maintaining tissue architecture, especially in epithelial and endothelial cells. PTPRM interacts with cadherins and catenins to regulate cell adhesion and cytoskeletal organization. Loss or downregulation of PTPRM is associated with cancer progression and metastasis due to disrupted cell adhesion. Its regulatory role in neuronal guidance and tissue integrity also highlights its importance in development and cancer biology.

Características del producto

category

ELISA Kits


immunogen target

Receptor-type tyrosine-protein phosphatase mu (PTPRM)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


alias

RPTPM,RPTPU,PTPRL1,hR-PTPu,R-PTP-MU,Protein-tyrosine phosphatase mu,Receptor-type tyrosine-protein phosphatase mu


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

PTPRM


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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