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Precio
687.5€ (96 tests)
Mouse Purinergic Receptor P2Y, G Protein Coupled 1 (P2RY1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Purinergic Receptor P2Y, G Protein Coupled 1 (P2RY1) concentrations in tissue homogenates, cell lysates and other biological fluids.
P2RY1 is a G protein-coupled receptor (GPCR) that binds extracellular nucleotides such as ADP, acting as a key player in platelet aggregation, neurotransmission, and vascular tone. It couples to Gq proteins, activating phospholipase C (PLC) and increasing intracellular calcium levels, which triggers platelet activation and aggregation in response to ADP. P2RY1 is widely expressed in platelets, the central nervous system, and endothelial cells, where it regulates hemostasis, blood clot formation, and vasodilation. In the CNS, P2RY1 modulates neuronal excitability and synaptic transmission. Dysregulation of P2RY1 signaling is associated with thrombosis, stroke, and neuroinflammatory conditions. P2RY1 antagonists are being developed as antithrombotic agents to prevent clot formation in cardiovascular diseases. Its critical role in platelet function, vascular regulation, and neuroprotection highlights P2RY1 as a therapeutic target for thrombotic disorders and neurological diseases.
ELISA Kits
P2Y Purinoceptor 1 (P2RY1)
Mouse
0.156 ng/ml - 10 ng/ml
Quantitative
Colorimetric
Tissue homogenates,Cell lysates,Other biological fluids
96 tests
P2RY1,ATP receptor,P2 purinoceptor subtype Y1,P2Y purinoceptor 1,platelet ADP receptor ,Purinergic receptor P2Y1,P2Y ATP receptor 1,P2Y1 receptor,purinergic receptor P2Y,P2Y1, SARCC
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
P2RY1
No
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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