Mouse Protein Tyrosine Phosphatase Receptor Type K (PTPRK) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits PTPRK
proveedor
Abbexareference
abx390345Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Protein Tyrosine Phosphatase Receptor Type K (PTPRK) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse PTPRK concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
PTPRK is a receptor-type protein tyrosine phosphatase involved in cell adhesion, contact inhibition, and tumor suppression. Structurally, it consists of an extracellular region with multiple immunoglobulin-like (Ig) and fibronectin type III domains, a single transmembrane domain, and two intracellular phosphatase domains, where the first is catalytically active. PTPRK is predominantly expressed in epithelial tissues and the immune system. It plays a key role in regulating β-catenin signaling, which is critical for maintaining cell adhesion and inhibiting proliferation. PTPRK has been identified as a tumor suppressor, and its downregulation or loss has been associated with colorectal, lung, and breast cancers. It also participates in immune cell development, particularly T-cell maturation. By dephosphorylating key tyrosine kinases and adhesion molecules, PTPRK maintains cellular homeostasis and tissue integrity.
Características del producto
category
ELISA Kits
immunogen target
Protein Tyrosine Phosphatase Receptor Type K (PTPRK)
reactivity
Mouse
test range
78 pg/ml - 5000 pg/ml
sensitivity
< 46.9 pg/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
R-PTP-kappa,PTPK,Protein-tyrosine phosphatase kappa,Receptor-type tyrosine-protein phosphatase kappa
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
PTPRK
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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