Mouse Protein Tyrosine Phosphatase Receptor Type K (PTPRK) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Protein Tyrosine Phosphatase Receptor Type K (PTPRK) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx390345
tested applications
ELISA
Description
Mouse Protein Tyrosine Phosphatase Receptor Type K (PTPRK) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse PTPRK concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Protein Tyrosine Phosphatase Receptor Type K (PTPRK) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 78 pg/ml - 5000 pg/ml |
| Sensitivity | < 46.9 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P35822 |
| Gene ID | 19272 |
| Alias | R-PTP-kappa,PTPK,Protein-tyrosine phosphatase kappa,Receptor-type tyrosine-protein phosphatase kappa |
| Background | Elisa kits for PTPRK |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
PTPRK is a receptor-type protein tyrosine phosphatase involved in cell adhesion, contact inhibition, and tumor suppression. Structurally, it consists of an extracellular region with multiple immunoglobulin-like (Ig) and fibronectin type III domains, a single transmembrane domain, and two intracellular phosphatase domains, where the first is catalytically active. PTPRK is predominantly expressed in epithelial tissues and the immune system. It plays a key role in regulating β-catenin signaling, which is critical for maintaining cell adhesion and inhibiting proliferation. PTPRK has been identified as a tumor suppressor, and its downregulation or loss has been associated with colorectal, lung, and breast cancers. It also participates in immune cell development, particularly T-cell maturation. By dephosphorylating key tyrosine kinases and adhesion molecules, PTPRK maintains cellular homeostasis and tissue integrity.
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