Mouse Protein BRICK1 (BRK1) ELISA Kit

Este producto es parte de BRK1 - BRICK1 subunit of SCAR/WAVE actin nucleating complex
Mouse Protein BRICK1 (BRK1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

728€ (96 tests)

Elisa kits for BRK1

proveedor

Abbexa

reference

abx388714

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Protein BRICK1 (BRK1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Protein BRICK1 (BRK1) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

BRICK1 subunit of SCAR/WAVE actin nucleating complex (BRK1) is a protein that is a part of the SCAR/WAVE complex, which regulates actin polymerization by activating the Arp2/3 complex The SCAR/WAVE complex, including BRICK1, is involved in initiating the formation of branched actin filaments, a process essential for cell movement, membrane ruffling, and cellular shape changes BRICK1 plays a role in promoting actin dynamics, particularly in immune cells where it influences processes such as T-cell activation, cell migration, and phagocytosis In addition, BRICK1 is important for neuronal development, where it helps regulate synaptic plasticity and dendritic spine morphology Disruption of BRICK1 or the SCAR/WAVE complex can lead to defects in cell motility, immune function, and nervous system development Abnormal regulation of actin dynamics due to BRICK1 dysfunction is implicated in various diseases, including autoimmune disorders, cancer metastasis, and neurodevelopmental disorders where impaired cellular movement and actin remodeling contribute to disease progression

Características del producto

category

ELISA Kits


immunogen target

Protein BRICK1 (BRK1)


reactivity

Mouse


test range

0.312 ng/ml - 20 ng/ml


sensitivity

< 0.12 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

MDS027,hHBrk1,C3orf10,HSPC300,Protein BRICK4


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

BRK1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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