Mouse Prostaglandin F2 Receptor Negative Regulator (PTGFRN) Protein

Este producto es parte de PTGFRN - prostaglandin F2 receptor inhibitor
Product Graph
221€ (10 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Mouse Prostaglandin F2 Receptor Negative Regulator (PTGFRN) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168749
tested applications
WB, SDS-PAGE

Description

Mouse PTGFRN Protein is a recombinant Mouse protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Prostaglandin F2 Receptor Negative Regulator (PTGFRN)
Host
E. coli
Assay Type
Activity: Not tested
Sequence Fragment: Arg22-Gln263
Tag: N-terminal His tag
Origin
Mouse
Conjugation
Unconjugated
Observed MW
Calculated MW: 30.5 kDa  Observed MW (SDS-PAGE): 31 kDa
Expression
Recombinant
Purity
> 97%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose.
Availability
Shipped within 5-7 working days.
Storage
Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles.
Dry Ice
No
UniProt ID
Q9WV91
Alias
Prostaglandin F2 receptor negative regulator,FPRP,CD315,EWI-F,CD9P-1,SMAP-6,CD9 partner 1,Glu-Trp-Ile EWI motif-containing protein F
Background
Protein PTGFRN
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Concentration: Prior to lyophilization: 250 µg/ml

Descripción

Prostaglandin F2 receptor inhibitor (PTGFRN), also known as CD315 or FPRP (Fas-associated protein response-related protein), is a transmembrane protein associated with prostaglandin receptor signaling. PTGFRN is known primarily for its ability to modulate prostaglandin F2 alpha (PGF2α) receptor function, thereby impacting prostaglandin signaling pathways involved in inflammatory responses, immune modulation, and reproductive processes. PTGFRN doesn’t directly bind prostaglandins but instead influences PGF2α receptor function indirectly, regulating cellular responses to prostaglandins by modifying receptor sensitivity and availability on the cell surface. PTGFRN has a wide tissue distribution and is expressed in cells of the immune system, cardiovascular tissues, reproductive organs, and certain epithelial tissues. Its role extends beyond prostaglandin modulation, as it’s also involved in various cellular processes including cell adhesion, migration, and interactions with other membrane proteins, such as tetraspanins. PTGFRN is therefore relevant in inflammatory diseases, reproductive health, cardiovascular function, and potentially in cancer.

Related Products

abx030330

Prostaglandin F2 Receptor Negative Regulator (PTGFRN) Antibody

PTGFRN inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity).

Ver Producto
abx130830

Prostaglandin F2 Receptor Negative Regulator (PTGFRN) Antibody

PTGFRN Antibody is a Rabbit Polyclonal against PTGFRN.

Ver Producto
abx130831

Prostaglandin F2 Receptor Negative Regulator (PTGFRN) Antibody

PTGFRN Antibody is a Rabbit Polyclonal against PTGFRN.

Ver Producto