Mouse Prostaglandin F2 Receptor Negative Regulator (PTGFRN) Protein

221€ (10 µg)
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935106861
info@markelab.com
name
Mouse Prostaglandin F2 Receptor Negative Regulator (PTGFRN) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168749
tested applications
WB, SDS-PAGE
Description
Mouse PTGFRN Protein is a recombinant Mouse protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Prostaglandin F2 Receptor Negative Regulator (PTGFRN) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Arg22-Gln263 Tag: N-terminal His tag |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 30.5 kDa Observed MW (SDS-PAGE): 31 kDa |
| Expression | Recombinant |
| Purity | > 97% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9WV91 |
| Alias | Prostaglandin F2 receptor negative regulator,FPRP,CD315,EWI-F,CD9P-1,SMAP-6,CD9 partner 1,Glu-Trp-Ile EWI motif-containing protein F |
| Background | Protein PTGFRN |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 250 µg/ml |
Descripción
Prostaglandin F2 receptor inhibitor (PTGFRN), also known as CD315 or FPRP (Fas-associated protein response-related protein), is a transmembrane protein associated with prostaglandin receptor signaling. PTGFRN is known primarily for its ability to modulate prostaglandin F2 alpha (PGF2α) receptor function, thereby impacting prostaglandin signaling pathways involved in inflammatory responses, immune modulation, and reproductive processes. PTGFRN doesn’t directly bind prostaglandins but instead influences PGF2α receptor function indirectly, regulating cellular responses to prostaglandins by modifying receptor sensitivity and availability on the cell surface. PTGFRN has a wide tissue distribution and is expressed in cells of the immune system, cardiovascular tissues, reproductive organs, and certain epithelial tissues. Its role extends beyond prostaglandin modulation, as it’s also involved in various cellular processes including cell adhesion, migration, and interactions with other membrane proteins, such as tetraspanins. PTGFRN is therefore relevant in inflammatory diseases, reproductive health, cardiovascular function, and potentially in cancer.
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