Mouse Prostaglandin D2 receptor (PTGDR) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for PTGDR
proveedor
Abbexareference
abx517362Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Prostaglandin D2 receptor (PTGDR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Prostaglandin D2 receptor concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
PTGDR, also known as DP1, is a G protein-coupled receptor (GPCR) that binds prostaglandin D2 (PGD2), a lipid mediator involved in allergic inflammation, immune regulation, and sleep. PTGDR primarily couples to Gs proteins, activating adenylate cyclase, which increases intracellular cAMP levels, leading to downstream effects such as vasodilation, inhibition of platelet aggregation, and modulation of immune cell activity. PTGDR is expressed in mast cells, Th2 lymphocytes, and airway epithelial cells, where it plays a role in allergic diseases such as asthma, allergic rhinitis, and atopic dermatitis. Activation of PTGDR promotes smooth muscle relaxation, mucus production, and chemotaxis of immune cells during inflammation. Dysregulation of PTGDR is implicated in chronic allergic inflammation and respiratory disorders. PTGDR antagonists are being explored for treating asthma and other Th2-driven allergic conditions by reducing PGD2-mediated inflammation and immune responses.
Características del producto
category
ELISA Kits
immunogen target
Prostaglandin D2 receptor (PTGDR)
reactivity
Mouse
test range
0.625 ng/ml - 40 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
PTGDR,DP1,prostanoid DP receptor-like,PTGDR1,prostaglandin D2 receptor,AS1,ASRT1,DP,DP11
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
PTGDR
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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