Human Prostaglandin D2 receptor (PTGDR) ELISA Kit

Name: Human Prostaglandin D2 receptor (PTGDR) ELISA Kit
Brand: Abbexa
SKU: abx251006
Price: 715 EUR
Availability: OnlineOnly

Este producto es parte de PTGR - Prostaglandin receptor

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for PTGDR

proveedor

Abbexa

reference

abx251006

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Prostaglandin D2 receptor (PTGDR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Prostaglandin D2 receptor concentrations in tissue homogenates, cell lysates and other biological fluids.

Background

PTGDR, also known as DP1, is a G protein-coupled receptor (GPCR) that binds prostaglandin D2 (PGD2), a lipid mediator involved in allergic inflammation, immune regulation, and sleep. PTGDR primarily couples to Gs proteins, activating adenylate cyclase, which increases intracellular cAMP levels, leading to downstream effects such as vasodilation, inhibition of platelet aggregation, and modulation of immune cell activity. PTGDR is expressed in mast cells, Th2 lymphocytes, and airway epithelial cells, where it plays a role in allergic diseases such as asthma, allergic rhinitis, and atopic dermatitis. Activation of PTGDR promotes smooth muscle relaxation, mucus production, and chemotaxis of immune cells during inflammation. Dysregulation of PTGDR is implicated in chronic allergic inflammation and respiratory disorders. PTGDR antagonists are being explored for treating asthma and other Th2-driven allergic conditions by reducing PGD2-mediated inflammation and immune responses.

Características del producto

immunogen target

Prostaglandin D2 receptor (PTGDR)

reactivity

Human

test range

0.156 ng/ml - 10 ng/ml

assay type

Sandwich

assay data

Quantitative

form

Lyophilized

detection method

Colorimetric

sample type

Tissue homogenates, cell lysates and other biological fluids.

size 1

96 tests

alias

PTGDR,DP1,prostanoid DP receptor-like,PTGDR1,prostaglandin D2 receptor,AS1,ASRT1,DP,DP11

storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

or code

PTGDR

dry ice

uniprot id

https://www.uniprot.org/uniprotkb/Q13258

note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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reference

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reactivity

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status

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