Mouse Probable G-protein coupled receptor 37 (GPR37) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for GPR37
proveedor
Abbexareference
abx526020Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Probable G-protein coupled receptor 37 (GPR37) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Probable G-protein coupled receptor 37 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
GPR37, also known as the parkin receptor, is a G protein-coupled receptor expressed primarily in the brain, particularly in dopaminergic neurons. GPR37 plays an important role in regulating neuronal signaling, synaptic plasticity, and neuroinflammation. It is activated by its endogenous ligand, which remains largely unidentified, and couples to Gi proteins, leading to the inhibition of adenylate cyclase and modulation of other intracellular signaling pathways. GPR37 is involved in the pathophysiology of Parkinson's disease, as it is associated with the parkin gene, which is implicated in the degeneration of dopaminergic neurons. Mutations in the GPR37 gene have been linked to various neurodegenerative diseases, making this receptor an interesting target for therapeutic research. The receptor's potential as a modulator of neuroinflammation and neuronal survival is being explored for new treatments aimed at neurodegenerative diseases such as Parkinson’s.
Características del producto
category
ELISA Kits
immunogen target
Probable G-protein coupled receptor 37 (GPR37)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
GPR37,EDNRBL,EDNRLB,PAELR,G-protein coupled receptor CNS1,parkin-associated endothelin B-like receptor,Endothelin B receptor-like protein 1,hET(B)R-LP
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
GPR37
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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