G Protein Coupled Receptor 37 (GPR37) Antibody

Este producto es parte de GPR37 - G Protein Coupled Receptor
G Protein Coupled Receptor 37 (GPR37) Antibody

Pida mas información

935106861

info@markelab.com

Precio

612.5€ (100 µl)

Antibody anti-GPR37

proveedor

Abbexa

reference

abx112638

Tested Applications

ELISA, WB

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

Descripción

G Protein-Coupled Receptor 37 (Endothelin Receptor Type B-Like) Antibody is a Rabbit Polyclonal antibody against G Protein-Coupled Receptor 37 (Endothelin Receptor Type B-Like).


Background

GPR37, also known as the parkin receptor, is a G protein-coupled receptor expressed primarily in the brain, particularly in dopaminergic neurons. GPR37 plays an important role in regulating neuronal signaling, synaptic plasticity, and neuroinflammation. It is activated by its endogenous ligand, which remains largely unidentified, and couples to Gi proteins, leading to the inhibition of adenylate cyclase and modulation of other intracellular signaling pathways. GPR37 is involved in the pathophysiology of Parkinson's disease, as it is associated with the parkin gene, which is implicated in the degeneration of dopaminergic neurons. Mutations in the GPR37 gene have been linked to various neurodegenerative diseases, making this receptor an interesting target for therapeutic research. The receptor's potential as a modulator of neuroinflammation and neuronal survival is being explored for new treatments aimed at neurodegenerative diseases such as Parkinson’s.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human, Mouse, Rat


immunogen target

G Protein Coupled Receptor 37 (GPR37)


host

Rabbit


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, WB


purification

Antigen Affinity Chromatography.


buffer

PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol.


size 1

100 µl


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

GPR37


dry ice

No


availability

Shipped within 5-10 working days.


alias

GPR37,EDNRBL,EDNRLB,PAELR,G-protein coupled receptor CNS1,parkin-associated endothelin B-like receptor,Endothelin B receptor-like protein 1,hET(B)R-LP


note

This product is for research use only.


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