G Protein Coupled Receptor 37 (GPR37) Antibody
Pida mas información
935106861
info@markelab.com
Precio
612.5€ (100 µl)
Antibody anti-GPR37
proveedor
Abbexareference
abx112638Tested Applications
ELISA, WBreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalDescripción
G Protein-Coupled Receptor 37 (Endothelin Receptor Type B-Like) Antibody is a Rabbit Polyclonal antibody against G Protein-Coupled Receptor 37 (Endothelin Receptor Type B-Like).
Background
GPR37, also known as the parkin receptor, is a G protein-coupled receptor expressed primarily in the brain, particularly in dopaminergic neurons. GPR37 plays an important role in regulating neuronal signaling, synaptic plasticity, and neuroinflammation. It is activated by its endogenous ligand, which remains largely unidentified, and couples to Gi proteins, leading to the inhibition of adenylate cyclase and modulation of other intracellular signaling pathways. GPR37 is involved in the pathophysiology of Parkinson's disease, as it is associated with the parkin gene, which is implicated in the degeneration of dopaminergic neurons. Mutations in the GPR37 gene have been linked to various neurodegenerative diseases, making this receptor an interesting target for therapeutic research. The receptor's potential as a modulator of neuroinflammation and neuronal survival is being explored for new treatments aimed at neurodegenerative diseases such as Parkinson’s.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse, Rat
immunogen target
G Protein Coupled Receptor 37 (GPR37)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purification
Antigen Affinity Chromatography.
buffer
PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol.
size 1
100 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
GPR37
dry ice
No
availability
Shipped within 5-10 working days.
alias
GPR37,EDNRBL,EDNRLB,PAELR,G-protein coupled receptor CNS1,parkin-associated endothelin B-like receptor,Endothelin B receptor-like protein 1,hET(B)R-LP
uniprot id
note
This product is for research use only.
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