Mouse Pigment Epithelium-Derived Factor / PEDF (SERPINF1) Protein

Este producto es parte de SERPINF1 - serpin family F member 1
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247€ (10 µg)

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935106861
info@markelab.com
name
Mouse Pigment Epithelium-Derived Factor / PEDF (SERPINF1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx068543
tested applications
WB, SDS-PAGE

Description

Mouse Pigment Epithelium-Derived Factor (PEDF) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

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Data sheet
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Product specifications

CategoryProteins and Peptides
Immunogen TargetPigment Epithelium-Derived Factor / PEDF (SERPINF1)
HostE. coli
OriginMouse
ConjugationUnconjugated
Observed MWMolecular Weight: Calculated MW: 51.1 kDa Observed MW (SDS-PAGE): 58 kDa Possible reasons why the actual band size differs from the predicted band size: 1. Splice variants. Alternative splicing may create different sized proteins from the same gene. 2. Relative charge. The composition of amino acids may affect the charge of the protein. 3. Post-translational modification. Phosphorylation, glycoslyation, methylation etc. may affect the band size. 4. Post-translational cleavage. Many proteins are synthesised as pro-proteins, and then cleaved to give the active form. 5. Polymerisation of the target protein. Dimerisation, multimerisation etc. will increase the band size observed. Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser19-Thr417 Tag: N-terminal His tag
ExpressionRecombinant
Purity> 97%
Size 110 µg
Size 250 µg
Size 3100 µg
Size 4200 µg
Size 5500 µg
FormLyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested ApplicationsWB, SDS-PAGE
BufferPrior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
AvailabilityShipped within 5-7 working days.
StorageStore at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDP97298
Gene ID20317
AliasOI6,OI12,PEDF,EPC-1,PIG35,Pigment epithelium-derived factor,Cell proliferation-inducing gene 35 protein,Serpin F1
BackgroundProtein SERPINF1
StatusRUO
NoteThis product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

SERPINF1, also known as pigment epithelium-derived factor (PEDF), is a member of the serpin (serine protease inhibitor) family, though it has unique properties distinct from classical serpins. Unlike most serpins, SERPINF1 does not function as a typical protease inhibitor but is instead a multifunctional protein with potent anti-angiogenic, neuroprotective, and anti-inflammatory effects. First identified in the pigment epithelium of the eye, it has since been found in a variety of tissues and is now recognized as a crucial player in many biological processes, including the inhibition of abnormal blood vessel growth and tissue protection. SERPINF1 is highly expressed in the eye, particularly in the retinal pigment epithelium (RPE) and other neural tissues. It is most famous for its role in ocular health, but its functions extend to other organs, such as the liver, heart, skin, and brain.

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