Mouse PHD finger protein 13 (PHF13) ELISA Kit
715€ (96 tests)
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935106861
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name
Mouse PHD finger protein 13 (PHF13) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx538653
tested applications
ELISA
Description
Mouse PHD finger protein 13 (PHF13) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse PHD finger protein 13 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | PHD finger protein 13 (PHF13) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8K2W6 |
| Gene ID | 230936 |
| Alias | PHF5,SPOC1 |
| Background | Elisa kits for PHF13 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
PHF13 is a chromatin-binding protein with a PHD finger domain that recognizes methylated histone residues, particularly H3K4me3, to regulate transcriptional activation and chromatin accessibility. It functions as a transcriptional co-activator, recruiting chromatin remodelers and transcription machinery to active gene loci. PHF13 is involved in processes such as DNA repair, cellular differentiation, and the regulation of pluripotency genes in embryonic stem cells. It is expressed in various tissues, including hematopoietic and neural lineages, where it modulates lineage-specific gene expression programs. Dysregulation of PHF13 has been associated with impaired DNA damage response, developmental defects, and tumorigenesis, where altered chromatin dynamics affect cellular proliferation and survival. Knockout studies demonstrate reduced transcriptional activation, defective chromatin remodeling, and impaired cellular differentiation, underscoring its role in maintaining transcriptional fidelity and chromatin structure during development and stress responses.
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