Mouse Neuropeptide Y Receptor Y5 (NPY5R) Protein

Este producto es parte de NPY - Neuropeptide Y Receptor
Product Graph
1872€ (1 mg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Mouse Neuropeptide Y Receptor Y5 (NPY5R) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx654540
tested applications
WB, SDS-PAGE

Description

Mouse Neuropeptide Y Receptor Y5 (NPY5R) Protein is a Recombinant Mouse protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Neuropeptide Y Receptor Y5 (NPY5R)
Host
E. coli
Origin
Mouse
Conjugation
Unconjugated
Observed MW
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Please enquire.
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 90%
Size 1
1 mg
Size 2
5 mg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 1-2 months.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
NPY5R,NPY5-R,NPYY5-R,ood intake receptor,neuropeptide Y receptor type 5
Background
Protein NPY5R
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

NPY5R is a G protein-coupled receptor that binds neuropeptide Y (NPY), peptide YY (PYY), and pancreatic polypeptide (PP). It is primarily expressed in the hypothalamus and limbic system, where it regulates appetite, energy homeostasis, and stress responses. NPY5R couples to Gi/o proteins, inhibiting adenylate cyclase and reducing cAMP levels, leading to modulation of neuronal signaling and feeding behavior. Activation of NPY5R promotes appetite stimulation and energy storage, playing a critical role in obesity and metabolic disorders. NPY5R also contributes to stress-related behaviors, anxiety, and cardiovascular regulation. Dysregulation of NPY5R signaling is associated with hyperphagia, obesity, and mood disorders. NPY5R antagonists are being explored as therapeutic agents to suppress appetite and reduce body weight in obesity. Its involvement in feeding behavior, stress regulation, and energy balance highlights NPY5R as a potential target for treating obesity, metabolic syndrome, and related mood disorders.

Related Products

EH3439

Human NPYR5 (Neuropeptide Y Receptor Y5) ELISA Kit

Ver Producto
abx152552

Human Neuropeptide Y Receptor Y5 (NPY5R) ELISA Kit

Human Neuropeptide Y Receptor Y5 (NPY5R) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human NPY5R concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of NPY5R

Ver Producto
abx154473

Mouse Neuropeptide Y Receptor Y5 (NPY5R) ELISA Kit

Mouse Neuropeptide Y Receptor Y5 (NPY5R) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse NPY5R concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of NPY5R

Ver Producto