Mouse Neuropeptide Y receptor type 6 (NPY6R) ELISA Kit

Este producto es parte de NPY - Neuropeptide Y Receptor
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Neuropeptide Y receptor type 6 (NPY6R) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx535788
tested applications
ELISA

Description

Mouse Neuropeptide Y receptor type 6 (NPY6R) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Neuropeptide Y receptor type 6 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Neuropeptide Y receptor type 6 (NPY6R)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q61212
Gene ID
18169
Alias
NPY6R,PP2,Y2B,NPY1RL,NPY6RP,Y5,Pancreatic polypeptide receptor 2,PP2
Background
Elisa kits for NPY6R
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

NPY6R is a non-functional neuropeptide Y receptor in humans due to genetic inactivation; however, it remains functional in certain other species. In functional contexts, NPY6R binds neuropeptide Y (NPY) and peptide YY (PYY), acting as a regulator of energy homeostasis, feeding behavior, and metabolic responses. Its signaling is thought to couple to Gi/o proteins, inhibiting adenylate cyclase and reducing cAMP levels, similar to other NPY receptors. While non-functional in humans, NPY6R’s evolutionary remnants suggest a historical role in appetite and energy regulation. Its absence in humans highlights compensatory mechanisms involving other NPY receptors, such as NPY1R, NPY2R, and NPY5R, which maintain neuropeptide-mediated regulation of feeding, energy balance, and stress responses. Understanding NPY6R’s evolutionary divergence provides insights into species-specific differences in neuropeptide signaling and its role in energy regulation.

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