Mouse Neuronal Growth Regulator 1 (NEGR1) Protein
1235€ (100 µg)
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935106861
info@markelab.com
name
Mouse Neuronal Growth Regulator 1 (NEGR1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691605
tested applications
SDS-PAGE
Description
Mouse NEGR1 Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the mouse NEGR1 (NP_001034183.1) (Met 1-Gly 318) without the pro peptide was expressed, with a C-terminal polyhistidine tag.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | NEGR1 |
| Host | HEK293 cells |
| Origin | Mouse |
| Observed MW | Molecular Weight: 33 kDa Sequence Fragment: Met1-Gly318 Tag: C-terminal His tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 94% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NP_001034183.1 |
| Alias | Ntra,KILON,IGLON4,DMML2433,IgLON family member 4 |
| Background | Protein NEGR1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Neuronal Growth Regulator 1 (NEGR1) is a glycosylphosphatidylinositol (GPI)-anchored protein that plays a critical role in brain development, particularly in processes involving cell adhesion, synapse formation, and neuronal connectivity. It is a member of the immunoglobulin superfamily and is predominantly expressed in the central nervous system. NEGR1 contributes to neuronal growth and synaptic plasticity, influencing cognitive functions such as learning and memory. It is also implicated in regulating neuronal migration and axon guidance during development. Variants or altered expression of NEGR1 have been associated with neuropsychiatric conditions, including autism spectrum disorders, schizophrenia, and depression, underlining its importance in maintaining normal brain function. As a potential biomarker and therapeutic target, NEGR1 continues to be a focus of research in neurodevelopmental and psychiatric disease studies.
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