Mouse Meteorin (METRN) Protein

Este producto es parte de METRN - Meteorin (Like)
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1118€ (50 µg)

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935106861
info@markelab.com
name
Mouse Meteorin (METRN) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx693068
tested applications
SDS-PAGE

Description

Meteorin (METRN) protein is a recombinant Mouse protein expressed in HEK293 cells.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Meteorin (METRN)
Host
HEK293 cells
Assay Type
Activity: Not tested
Sequence Fragment: Gly22-Asp291
Tag: N-terminal Fc tag
Origin
Mouse
Observed MW
58.4 kDa
Expression
Recombinant
Purity
> 85% (SDS-PAGE)
Size 1
50 µg
Form
Lyophilized
Tested Applications
SDS-PAGE
Buffer
Prior to lyophilization: Sterile PBS, pH 7.4.
Availability
Shipped within 5-15 working days.
Storage
Storage: Store lyophilized between -20 °C and -80°C.
Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months.
Shelf Life: 12 months.
Dry Ice
No
UniProt ID
Q8C1Q4-1
Alias
glial cell differentiation regulator,C16orf23,c380A1.2
Background
Protein METRN
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Endotoxin Level: < 1.0 EU per µg (LAL method).

Descripción

Meteorin, encoded by the METRN gene, is a secreted protein primarily involved in neural and glial cell differentiation and regeneration. METRN is expressed in the nervous system and functions as a neurotrophic factor, promoting neurite outgrowth and supporting the survival of glial progenitor cells. It is also implicated in modulating inflammatory responses in the central nervous system (CNS), playing a protective role in neurodegenerative diseases and brain injuries. Meteorin activates the Jak/STAT and PI3K/Akt signaling pathways to exert its biological effects, including promoting astrocyte differentiation and maintaining the blood-brain barrier's integrity. Emerging studies suggest that METRN may also have a role in muscle regeneration and metabolic regulation, expanding its functional repertoire beyond the CNS.

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