Mouse Meteorin (METRN) Protein
1079€ (50 µg)
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935106861
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name
Mouse Meteorin (METRN) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx693068
tested applications
SDS-PAGE
Description
Mouse Meteorin Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the mouse METRN (Q8C1Q4-1) (Gly22-Asp291) was expressed with the fused Fc region of human IgG1 at the N-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Meteorin |
| Host | HEK293 cells |
| Origin | Mouse |
| Observed MW | Molecular Weight: 58.4 kDa Sequence Fragment: Gly22-Asp291 Tag: N-terminal Fc tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 85% (SDS-PAGE) |
| Size 1 | 50 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8C1Q4-1 |
| Alias | glial cell differentiation regulator,C16orf23,c380A1.2 |
| Background | Protein METRN |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Meteorin, encoded by the METRN gene, is a secreted protein primarily involved in neural and glial cell differentiation and regeneration. METRN is expressed in the nervous system and functions as a neurotrophic factor, promoting neurite outgrowth and supporting the survival of glial progenitor cells. It is also implicated in modulating inflammatory responses in the central nervous system (CNS), playing a protective role in neurodegenerative diseases and brain injuries. Meteorin activates the Jak/STAT and PI3K/Akt signaling pathways to exert its biological effects, including promoting astrocyte differentiation and maintaining the blood-brain barrier's integrity. Emerging studies suggest that METRN may also have a role in muscle regeneration and metabolic regulation, expanding its functional repertoire beyond the CNS.
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