935106861
info@markelab.com
Precio
687.5€ (96 tests)
Mouse Lysophosphatidic Acid Receptor 4 (LPAR4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Lysophosphatidic acid receptor 4 concentrations in tissue homogenates, cell lysates and other biological fluids.
LPAR4 is a G protein-coupled receptor for lysophosphatidic acid (LPA) that preferentially couples to G12/13 and Gq proteins, influencing cytoskeletal organization, calcium signaling, and cell migration. LPAR4 is expressed in hematopoietic cells, endothelial cells, and certain epithelial tissues, where it regulates cell adhesion, proliferation, and vascular development. Unlike other LPA receptors, LPAR4 has been implicated in blood vessel stability and lymphocyte trafficking, playing a role in vascular homeostasis and immune cell regulation. LPAR4 activation contributes to endothelial barrier function and vascular remodeling, making it relevant in conditions such as vascular inflammation and atherosclerosis. In cancer, LPAR4’s role is less well characterized compared to other LPA receptors, but it has been linked to cell migration and metastasis in certain malignancies. Dysregulation of LPAR4 signaling is associated with vascular disorders and immune dysfunction. Targeting LPAR4 offers therapeutic potential for vascular diseases, immune modulation, and cancer progression, highlighting its emerging role in LPA-mediated signaling pathways.
ELISA Kits
Lysophosphatidic Acid Receptor 4 (LPAR4)
Mouse
0.156 ng/ml - 10 ng/ml
< 0.082 ng/ml
Sandwich
Quantitative
Colorimetric
Tissue homogenates,Cell lysates,Other biological fluids
96 tests
LPAR4,GPR23,LPA4,P2RY9,P2Y5-LIKE,P2Y9,P2Y5-like receptor,G protein-coupled receptor 23,LPA receptor 4,P2Y,purinoceptor 9,Purinergic receptor 9
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
LPAR4
No
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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