Human LPAR4(Lysophosphatidic acid receptor 4) ELISA Kit
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name
Human LPAR4(Lysophosphatidic acid receptor 4) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH0990
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.313-20ng/ml |
| Size 1 | 96T |
| Sample Type | Serum,Plasma,Tissue homogenates,Other biological fluids |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 6 months |
| UniProt ID | Q99677 |
| Alias | LPAR4,GPR23,LPA4,P2RY9,P2Y5-LIKE,P2Y9,P2Y5-like receptor,G protein-coupled receptor 23,LPA receptor 4,P2Y,purinoceptor 9,Purinergic receptor 9 |
| Background | Elisa Kits LPAR4 |
| Status | RUO |
LPAR4 is a G protein-coupled receptor for lysophosphatidic acid (LPA) that preferentially couples to G12/13 and Gq proteins, influencing cytoskeletal organization, calcium signaling, and cell migration. LPAR4 is expressed in hematopoietic cells, endothelial cells, and certain epithelial tissues, where it regulates cell adhesion, proliferation, and vascular development. Unlike other LPA receptors, LPAR4 has been implicated in blood vessel stability and lymphocyte trafficking, playing a role in vascular homeostasis and immune cell regulation. LPAR4 activation contributes to endothelial barrier function and vascular remodeling, making it relevant in conditions such as vascular inflammation and atherosclerosis. In cancer, LPAR4’s role is less well characterized compared to other LPA receptors, but it has been linked to cell migration and metastasis in certain malignancies. Dysregulation of LPAR4 signaling is associated with vascular disorders and immune dysfunction. Targeting LPAR4 offers therapeutic potential for vascular diseases, immune modulation, and cancer progression, highlighting its emerging role in LPA-mediated signaling pathways.
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anti- LPAR4 antibody
Receptor for lysophosphatidic acid(LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl-> 1-stearoyl-> 1-palmitoyl-> 1-myristoyl-> 1-alkyl-> 1-alkenyl-LPA.
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