Mouse Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A (FCGR3A) Protein (Active)

Este producto es parte de FCGR3A - Fc gamma receptor IIIa
Product Graph
247€ (10 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Mouse Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A (FCGR3A) Protein (Active)
category
Proteins and Peptides
provider
Abbexa
reference
abx690241
tested applications
SDS-PAGE

Description

Mouse Low affinity IgG Fc receptor III Protein is a recombinant protein from Mouse produced in Human Cells. Recombinant Mouse Low affinity IgG Fc receptor III is produced by our Mammalian expression system and the target gene encoding Ala31-Thr215 is expressed with a 6His tag at the C-terminus.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Low affinity IgG Fc receptor III
Host
Human
Origin
Mouse
Observed MW
Molecular Weight: 22 kDa
Sequence Fragment: Met1-Thr215
Tag: C-terminal 6 His tag
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
10 µg
Size 2
50 µg
Form
Lyophilized 
Tested Applications
SDS-PAGE
Buffer
PBS, pH7.4.
Availability
Shipped within 5-15 working days.
Storage
Store at < -20°C.
Dry Ice
No
UniProt ID
P08508-1
Alias
CD16,FCG3,CD16A,FCGR3,IGFR3,IMD20,FCR-10,FCRIII,CD16-II,FCGRIII,FCRIIIA,FcGRIIIA,Low affinity immunoglobulin gamma Fc region receptor III-A,IgG Fc receptor III-A,IgG Fc receptor III-2
Background
Protein FCGR3A
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

FCGR3A, or Fc gamma receptor IIIa, is a membrane-bound protein that plays a crucial role in the immune system, specifically in mediating immune responses through the recognition of the Fc region of IgG antibodies. This receptor is primarily expressed on the surface of natural killer (NK) cells, macrophages, monocytes, and dendritic cells, where it facilitates antibody-dependent cellular cytotoxicity (ADCC) and other immune responses. It is part of the broader family of Fc gamma receptors (FcγRs), which are responsible for binding to the Fc region of IgG antibodies, thereby linking humoral and cellular immunity. FCGR3A has garnered considerable attention in immunology due to its role in recognizing and responding to immune complexes, infected cells, and tumor cells coated with IgG antibodies. Variations in the gene encoding FCGR3A have been implicated in differential responses to infections, autoimmune diseases, and cancer therapies

Related Products

APC-30061

APC Anti-Human CD16(3G8)

Ver Producto
APC-30106

APC Anti-Mouse CD16/32 Antibody(2.4G2)

Ver Producto
F488-30061

FineTest®488 Anti-Human CD16(3G8)

Ver Producto