Mouse Long-chain-fatty-acid--CoA ligase 3 (ACSL3) ELISA Kit
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Description
Mouse Long-chain-fatty-acid--CoA ligase 3 (ACSL3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Long-chain-fatty-acid--CoA ligase 3 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Long-chain-fatty-acid--CoA ligase 3 (ACSL3) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9CZW4 |
| Gene ID | 74205 |
| Alias | ACS3,FACL3,LACS 3,LACS3 |
| Background | Elisa kits for ACSL3 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ACSL3 is a long-chain acyl-CoA synthetase that catalyzes the activation of long-chain fatty acids by converting them into acyl-CoA derivatives, facilitating their utilization in β-oxidation, lipid storage, and biosynthesis pathways. ACSL3 is widely expressed in various tissues, with a notable presence in the brain, lungs, and adipose tissue, where it plays a pivotal role in maintaining lipid homeostasis and energy production. It is particularly important in lipid droplet formation, regulating the storage of triglycerides and phospholipids. Additionally, ACSL3 is involved in modulating lipid signaling molecules, such as arachidonic acid, which influence inflammatory and cellular processes. Dysregulation of ACSL3 has been associated with metabolic disorders, cancer, and neurodegenerative diseases, highlighting its role in both energy metabolism and cellular signaling. Its activity ensures the proper distribution and use of fatty acids, making it essential for lipid-mediated cellular functions.
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