Acyl-CoA Synthetase Long-Chain Family Member 3 (ACSL3) Antibody
637€ (100 µl)
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Name
Acyl-CoA Synthetase Long-Chain Family Member 3 (ACSL3) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx110795
Tested Applications
ELISA, WB, IF/ICC
Description
Acyl-Coa Synthetase Long-Chain Family Member 3 Antibody is a Rabbit Polyclonal antibody against Acyl-Coa Synthetase Long-Chain Family Member 3.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Acyl-CoA Synthetase Long-Chain Family Member 3 (ACSL3) Immunogen: Human ACSL3. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O95573 |
| Gene ID | 2181 |
| OMIM | 602371 |
| Alias | ACS3,FACL3,LACS 3,LACS3 |
| Background | Antibody anti-ACSL3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ACSL3 is a long-chain acyl-CoA synthetase that catalyzes the activation of long-chain fatty acids by converting them into acyl-CoA derivatives, facilitating their utilization in β-oxidation, lipid storage, and biosynthesis pathways. ACSL3 is widely expressed in various tissues, with a notable presence in the brain, lungs, and adipose tissue, where it plays a pivotal role in maintaining lipid homeostasis and energy production. It is particularly important in lipid droplet formation, regulating the storage of triglycerides and phospholipids. Additionally, ACSL3 is involved in modulating lipid signaling molecules, such as arachidonic acid, which influence inflammatory and cellular processes. Dysregulation of ACSL3 has been associated with metabolic disorders, cancer, and neurodegenerative diseases, highlighting its role in both energy metabolism and cellular signaling. Its activity ensures the proper distribution and use of fatty acids, making it essential for lipid-mediated cellular functions.
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