Mouse Long-chain-fatty-acid--CoA ligase 1 (ACSL1) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Long-chain-fatty-acid--CoA ligase 1 (ACSL1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx500876
tested applications
ELISA
Description
Mouse Long-chain-fatty-acid--CoA ligase 1 (ACSL1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Long-chain-fatty-acid--CoA ligase 1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Long-chain-fatty-acid--CoA ligase 1 (ACSL1) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P41216 |
| Gene ID | 14081 |
| Alias | ACS1,LACS,FACL1,FACL2,LACS1,LACS2 |
| Background | Elisa kits for ACSL1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ACSL1 is a long-chain acyl-CoA synthetase that activates long-chain fatty acids, converting them into acyl-CoA derivatives for use in β-oxidation, lipid biosynthesis, and signaling pathways. It is highly expressed in energy-demanding tissues such as the heart, liver, and skeletal muscle, where it supports fatty acid metabolism and energy production during fasting and exercise. ACSL1 is critical for directing fatty acids toward oxidation rather than storage, ensuring metabolic flexibility and maintaining energy balance. Its role extends to regulating lipid signaling molecules, such as eicosanoids, which mediate inflammation and other cellular responses. Dysregulation of ACSL1 has been implicated in metabolic disorders, including insulin resistance, diabetes, and non-alcoholic fatty liver disease, where impaired fatty acid activation contributes to disrupted energy homeostasis and lipid accumulation. ACSL1’s enzymatic activity and tissue-specific expression highlight its central role in coordinating lipid metabolism and systemic energy regulation.
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