Mouse Leukotriene B4 receptor 2 (LTB4R2) ELISA Kit
715€ (96 tests)
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935106861
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name
Mouse Leukotriene B4 receptor 2 (LTB4R2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx531683
tested applications
ELISA
Description
Mouse Leukotriene B4 receptor 2 (LTB4R2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Leukotriene B4 receptor 2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Leukotriene B4 receptor 2 (LTB4R2) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9JJL9 |
| Gene ID | 57260 |
| Alias | LTB4R2 |
| Background | Elisa kits for LTB4R2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
LTB4R2, also known as BLT2, is a low-affinity G protein-coupled receptor for leukotriene B4 (LTB4) but can also bind other bioactive lipids, such as 12-hydroxyheptadecatrienoic acid (12-HHT). LTB4R2 is broadly expressed in various tissues, including immune cells, epithelial cells, and endothelial cells, where it mediates inflammation, immune responses, and tissue homeostasis. Compared to LTB4R1, LTB4R2 is involved in both pro-inflammatory and anti-inflammatory signaling, depending on the ligand and cellular context. LTB4R2 activation triggers downstream pathways such as PI3K/Akt and NF-κB, regulating cellular migration, ROS production, and cytokine release. In chronic inflammatory diseases like asthma, IBD, and arthritis, LTB4R2 contributes to tissue damage and immune cell recruitment. Interestingly, LTB4R2 also plays a protective role in epithelial barrier function and oxidative stress responses, highlighting its dual roles. Dysregulation of LTB4R2 signaling has been linked to cancer progression, metabolic disorders, and chronic inflammation. Targeting LTB4R2 represents a promising strategy for controlling inflammation and improving outcomes in inflammatory and oxidative stress-related diseases.
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