Mouse Leucine Rich Repeats And Immunoglobulin Like Domains Protein 3 (LRIG3) Protein
247€ (10 µg)
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935106861
info@markelab.com
name
Mouse Leucine Rich Repeats And Immunoglobulin Like Domains Protein 3 (LRIG3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx067760
tested applications
WB, SDS-PAGE
Description
Recombinant Leucine Rich Repeats And Immunoglobulin Like Domains Protein 3 (LRIG3) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Leucine Rich Repeats And Immunoglobulin Like Domains Protein 3 (LRIG3) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 30.9 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Asp866-Cys1110 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q6P1C6 |
| Alias | LIG3,LIG-3 |
| Background | Protein LRIG3 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
LRIG3 is another member of the LRIG family, with structural domains similar to LRIG1 and LRIG2. It is widely expressed in neural tissues, the vascular system, and other organs, where it influences cell signaling, development, and tissue organization. LRIG3 is thought to play a role in neuronal development by regulating axon guidance and synaptic plasticity. LRIG3 interacts with RTKs and extracellular matrix proteins, modulating signaling pathways related to growth and differentiation. LRIG3 is also involved in vascular remodeling and angiogenesis. Dysregulation of LRIG3 has been linked to congenital malformations and vascular diseases, as well as certain cancers, where it can promote or suppress tumorigenesis depending on the context. Further research is needed to clarify its exact roles in health and disease.
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