Mouse Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein 1 (LRIG1) Protein
234€ (2 µg)
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935106861
info@markelab.com
name
Mouse Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein 1 (LRIG1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx680167
tested applications
SDS-PAGE
Description
Mouse Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein 1 (LRIG1) Protein is a recombinant protein produced in Sf9, Baculovirus cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein 1 (LRIG1) |
| Host | Insect |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | P70193 |
| Gene ID | 16206 |
| Alias | LIG1,LIG-1 |
| Background | Protein LRIG1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
LRIG1 is a transmembrane protein characterized by leucine-rich repeats (LRRs) and immunoglobulin-like (Ig-like) domains, which mediate protein-protein interactions. LRIG1 is expressed in various tissues and plays a critical role in regulating cell growth, differentiation, and signaling pathways, particularly in epidermal and neural cells. LRIG1 acts as a negative regulator of receptor tyrosine kinases (RTKs), such as EGFR (epidermal growth factor receptor), by promoting their degradation. LRIG1 maintains stem cell homeostasis in epithelial tissues, such as the skin and intestines. Dysregulation of LRIG1 expression is linked to cancer progression, where its loss contributes to unchecked cell proliferation and metastasis. Conversely, high LRIG1 levels correlate with better prognosis in certain cancers. LRIG1 also regulates neuronal signaling and plasticity, highlighting its broad functional importance in both development and disease.
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