Mouse Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein 1 (LRIG1) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits LRIG1
proveedor
Abbexareference
abx531525Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Leucine-rich repeats and immunoglobulin-like domains protein 1 (LRIG1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Leucine-rich repeats and immunoglobulin-like domains protein 1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
LRIG1 is a transmembrane protein characterized by leucine-rich repeats (LRRs) and immunoglobulin-like (Ig-like) domains, which mediate protein-protein interactions. LRIG1 is expressed in various tissues and plays a critical role in regulating cell growth, differentiation, and signaling pathways, particularly in epidermal and neural cells. LRIG1 acts as a negative regulator of receptor tyrosine kinases (RTKs), such as EGFR (epidermal growth factor receptor), by promoting their degradation. LRIG1 maintains stem cell homeostasis in epithelial tissues, such as the skin and intestines. Dysregulation of LRIG1 expression is linked to cancer progression, where its loss contributes to unchecked cell proliferation and metastasis. Conversely, high LRIG1 levels correlate with better prognosis in certain cancers. LRIG1 also regulates neuronal signaling and plasticity, highlighting its broad functional importance in both development and disease.
Características del producto
category
ELISA Kits
immunogen target
Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein 1 (LRIG1)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
LIG1,LIG-1
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
LRIG1
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Quizá le pueda interesar
anti- LRIG1 antibody
proveedor
FineTestreference
FNab09953Tested Applications
ELISA, WBreactivity
human,mousestatus
RUOclonality
polyclonalPrecio a consultar
Ver másLeucine-Rich Repeats and Immunoglobulin-Like Domains Protein 1 (LRIG1) Antibody
proveedor
Abbexareference
abx031198Tested Applications
ELISA, WBreactivity
Mousestatus
RUOclonality
PolyclonalLRIG1 act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves ...
250€ (80 µl)
Ver másHuman Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein 1 (LRIG1) Protein
proveedor
Abbexareference
abx067759Tested Applications
WB, SDS-PAGEstatus
RUORecombinant Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein 1 (LRIG1) is a recombinant Human protein produc...
237.5€ (10 µg)
Ver más