Mouse Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein 1 (LRIG1) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein 1 (LRIG1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx531525
tested applications
ELISA
Description
Mouse Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein 1 (LRIG1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein 1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Leucine-Rich Repeats and Immunoglobulin-Like Domains Protein 1 (LRIG1) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.05 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P70193 |
| Gene ID | 16206 |
| Alias | LIG1,LIG-1 |
| Background | Elisa kits for LRIG1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
LRIG1 is a transmembrane protein characterized by leucine-rich repeats (LRRs) and immunoglobulin-like (Ig-like) domains, which mediate protein-protein interactions. LRIG1 is expressed in various tissues and plays a critical role in regulating cell growth, differentiation, and signaling pathways, particularly in epidermal and neural cells. LRIG1 acts as a negative regulator of receptor tyrosine kinases (RTKs), such as EGFR (epidermal growth factor receptor), by promoting their degradation. LRIG1 maintains stem cell homeostasis in epithelial tissues, such as the skin and intestines. Dysregulation of LRIG1 expression is linked to cancer progression, where its loss contributes to unchecked cell proliferation and metastasis. Conversely, high LRIG1 levels correlate with better prognosis in certain cancers. LRIG1 also regulates neuronal signaling and plasticity, highlighting its broad functional importance in both development and disease.
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