Mouse Leucine-rich repeat-containing protein 52 (LRRC52) ELISA Kit

Este producto es parte de LRRC - Leucine-rich repeat-containing protein
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Leucine-rich repeat-containing protein 52 (LRRC52) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx531432
tested applications
ELISA

Description

Mouse Leucine-rich repeat-containing protein 52 (LRRC52) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Leucine-rich repeat-containing protein 52 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Leucine-rich repeat-containing protein 52 (LRRC52)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q5M8M9
Gene ID
240899
Alias
BK channel auxiliary gamma subunit LRRC52
Background
Elisa kits for LRRC52
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

LRRC52 is an auxiliary subunit of large-conductance calcium-activated potassium (BK) channels predominantly expressed in smooth muscle tissues and neurons it modulates the gating properties of BK channels influencing their sensitivity to voltage and calcium signaling this regulation is critical for cellular excitability and processes such as smooth muscle contraction and neurotransmitter release LRRC52 has been implicated in the control of vascular tone and neuronal signaling playing a role in conditions such as hypertension and neurological disorders studies suggest its expression is essential for proper reproductive function as it regulates ion channel activity in sperm further research is exploring its role in diseases such as epilepsy and hypertension where BK channel dysfunction contributes to pathophysiology LRRC52's interactions with other channel subunits and its regulatory mechanisms are key areas of ongoing investigation aimed at identifying novel therapeutic strategies targeting ion channel dysregulation

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