935106861
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Precio
687.5€ (96 tests)
Human Leucine Rich Repeat Containing 52 (LRRC52) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human LRRC52 concentrations in tissue homogenates, cell lysates and other biological fluids.
LRRC52 is an auxiliary subunit of large-conductance calcium-activated potassium (BK) channels predominantly expressed in smooth muscle tissues and neurons it modulates the gating properties of BK channels influencing their sensitivity to voltage and calcium signaling this regulation is critical for cellular excitability and processes such as smooth muscle contraction and neurotransmitter release LRRC52 has been implicated in the control of vascular tone and neuronal signaling playing a role in conditions such as hypertension and neurological disorders studies suggest its expression is essential for proper reproductive function as it regulates ion channel activity in sperm further research is exploring its role in diseases such as epilepsy and hypertension where BK channel dysfunction contributes to pathophysiology LRRC52's interactions with other channel subunits and its regulatory mechanisms are key areas of ongoing investigation aimed at identifying novel therapeutic strategies targeting ion channel dysregulation
ELISA Kits
Leucine Rich Repeat Containing 52 (LRRC52)
Human
0.313 ng/ml - 20 ng/ml
< 0.188 ng/ml
Sandwich
Quantitative
Colorimetric
Tissue homogenates,Cell lysates,Other biological fluids
96 tests
BK channel auxiliary gamma subunit LRRC52
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
LRRC52
No
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel(BK alpha). Modulates gating ...
Precio a consultar
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