Human Leucine Rich Repeat Containing 52 (LRRC52) ELISA Kit

715€ (96 tests)
Este producto es parte de LRRC - Leucine-rich repeat-containing protein
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Leucine Rich Repeat Containing 52 (LRRC52) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx388321
tested applications
ELISA

Descripción del producto

Human Leucine Rich Repeat Containing 52 (LRRC52) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human LRRC52 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Especificaciones del producto

OMIM615218
AliasBK channel auxiliary gamma subunit LRRC52
Assay DataQuantitative
Assay TypeSandwich
AvailabilityShipped within 5-12 working days. The validity for this kit is 6 months.
BackgroundElisa kits for LRRC52
CategoryELISA Kits
Detection MethodColorimetric
Dry IceNo
FormLyophilized
Gene ID440699
Immunogen TargetLeucine Rich Repeat Containing 52 (LRRC52)
NameHuman Leucine Rich Repeat Containing 52 (LRRC52) ELISA Kit
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Price715
ProviderAbbexa
ReactivityHuman
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Referenceabx388321
Sample TypeTissue homogenates, cell lysates and other biological fluids.
Sensitivity< 0.188 ng/ml
Size 196 tests
StatusRUO
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Test Range0.313 ng/ml - 20 ng/ml
Tested ApplicationsELISA
UniProt IDQ8N7C0

Descripcion del producto en español

Background en español

LRRC52 is an auxiliary subunit of large-conductance calcium-activated potassium (BK) channels predominantly expressed in smooth muscle tissues and neurons it modulates the gating properties of BK channels influencing their sensitivity to voltage and calcium signaling this regulation is critical for cellular excitability and processes such as smooth muscle contraction and neurotransmitter release LRRC52 has been implicated in the control of vascular tone and neuronal signaling playing a role in conditions such as hypertension and neurological disorders studies suggest its expression is essential for proper reproductive function as it regulates ion channel activity in sperm further research is exploring its role in diseases such as epilepsy and hypertension where BK channel dysfunction contributes to pathophysiology LRRC52's interactions with other channel subunits and its regulatory mechanisms are key areas of ongoing investigation aimed at identifying novel therapeutic strategies targeting ion channel dysregulation

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