Leucine Rich Repeat Containing 52 (LRRC52) Antibody
292.5€ (80 µl)
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935106861
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name
Leucine Rich Repeat Containing 52 (LRRC52) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx032643
tested applications
ELISA, WB
Description
LRRC52 Antibody is a Rabbit Polyclonal antibody against LRRC52.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Leucine Rich Repeat Containing 52 (LRRC52) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8N7C0 |
| Alias | BK channel auxiliary gamma subunit LRRC52 |
| Background | Antibody anti-LRRC52 |
| Status | RUO |
Descripción
LRRC52 is an auxiliary subunit of large-conductance calcium-activated potassium (BK) channels predominantly expressed in smooth muscle tissues and neurons it modulates the gating properties of BK channels influencing their sensitivity to voltage and calcium signaling this regulation is critical for cellular excitability and processes such as smooth muscle contraction and neurotransmitter release LRRC52 has been implicated in the control of vascular tone and neuronal signaling playing a role in conditions such as hypertension and neurological disorders studies suggest its expression is essential for proper reproductive function as it regulates ion channel activity in sperm further research is exploring its role in diseases such as epilepsy and hypertension where BK channel dysfunction contributes to pathophysiology LRRC52's interactions with other channel subunits and its regulatory mechanisms are key areas of ongoing investigation aimed at identifying novel therapeutic strategies targeting ion channel dysregulation
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anti- LRRC52 antibody
Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel(BK alpha). Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium. KCNU1 channel auxiliary protein. May modulate KCNU1 gating properties.
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Leucine Rich Repeat Containing 52 (LRRC52) Antibody
LRRC52 Antibody is a Rabbit Polyclonal antibody against LRRC52.
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Leucine Rich Repeat Containing 52 (LRRC52) Antibody
LRRC52 Antibody is a Rabbit Polyclonal against LRRC52.
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