Mouse Leucine-rich repeat-containing protein 38 (LRRC38) ELISA Kit
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935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits LRRC38
proveedor
Abbexareference
abx531389Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Leucine-rich repeat-containing protein 38 (LRRC38) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Leucine-rich repeat-containing protein 38 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
LRRC38 is a regulatory protein primarily expressed in smooth and skeletal muscle tissues where it acts as an auxiliary subunit of large-conductance calcium-activated potassium (BK) channels it modulates the sensitivity of BK channels to calcium and voltage facilitating their role in maintaining cellular excitability and muscle function its activity is essential for processes such as smooth muscle contraction and neuronal signaling as it influences the gating properties of potassium channels studies suggest that LRRC38 plays a role in regulating blood pressure through its effects on vascular tone and in modulating neurotransmitter release in the nervous system emerging evidence links dysregulation of LRRC38 to conditions like hypertension and muscular dystrophy further research is exploring its potential as a therapeutic target for disorders associated with abnormal BK channel function and calcium signaling
Características del producto
category
ELISA Kits
immunogen target
Leucine-rich repeat-containing protein 38 (LRRC38)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
BK channel auxiliary gamma subunit LRRC38
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
LRRC38
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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