Name: Human Leucine-rich repeat-containing protein 38 (LRRC38) ELISA Kit
Brand: Abbexa
SKU: abx531388
Price: 687.5 EUR
Availability: OnlineOnly

Background

LRRC38 is a regulatory protein primarily expressed in smooth and skeletal muscle tissues where it acts as an auxiliary subunit of large-conductance calcium-activated potassium (BK) channels it modulates the sensitivity of BK channels to calcium and voltage facilitating their role in maintaining cellular excitability and muscle function its activity is essential for processes such as smooth muscle contraction and neuronal signaling as it influences the gating properties of potassium channels studies suggest that LRRC38 plays a role in regulating blood pressure through its effects on vascular tone and in modulating neurotransmitter release in the nervous system emerging evidence links dysregulation of LRRC38 to conditions like hypertension and muscular dystrophy further research is exploring its potential as a therapeutic target for disorders associated with abnormal BK channel function and calcium signaling

Características del producto

immunogen target

Leucine-rich repeat-containing protein 38 (LRRC38)

reactivity

Human

test range

0.156 ng/ml - 10 ng/ml

assay data

Quantitative

detection method

Colorimetric

sample type

Tissue homogenates,Cell lysates,Other biological fluids

size 1

96 tests

alias

BK channel auxiliary gamma subunit LRRC38

storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit

or code

LRRC38

dry ice

uniprot id

https://www.uniprot.org/uniprotkb/Q5VT99

note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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