Mouse KH domain-containing, RNA-binding, signal transduction-associated protein 2 (KHDRBS2) ELISA Kit

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Description
Mouse KH domain-containing, RNA-binding, signal transduction-associated protein 2 (KHDRBS2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse KH domain-containing, RNA-binding, signal transduction-associated protein 2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | KH domain-containing, RNA-binding, signal transduction-associated protein 2 (KHDRBS2) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9WU01 |
| Gene ID | 170771 |
| Alias | KHDRBS2-OT, KHDRBS2-OT1, SLM-1, SLM1,Sam68-like mammalian protein 1 |
| Background | Elisa Kits for: KHDRBS2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
KHDRBS2, also called SLIM-1 (Sam68-like mammalian protein 1), is a KH-domain-containing RNA-binding protein that regulates RNA splicing, transport, and translation. It functions downstream of receptor tyrosine kinases and cytoplasmic signaling pathways, linking RNA metabolism to cell signaling. KHDRBS2 is expressed predominantly in differentiated tissues, including the brain, where it regulates alternative splicing and mRNA stability of genes involved in neuronal differentiation, synaptic function, and cellular adhesion. It interacts with SH2-containing signaling proteins and participates in regulating processes like cellular differentiation and tissue-specific gene expression. Dysregulation of KHDRBS2 contributes to neurological disorders and has been implicated in tumor suppression by modulating growth-related mRNAs. Knockout models suggest its role in neuronal development and maintaining cellular homeostasis through mRNA regulation.
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