Mouse Junctional Adhesion Molecule A (F11R) Protein
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Description
Junctional Adhesion Molecule A (F11R) protein is a recombinant Mouse protein expressed in HEK293 cells.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Junctional Adhesion Molecule A (F11R) |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Ala242 Tag: C-terminal Fc tag |
| Origin | Mouse |
| Observed MW | 50.2 kDa |
| Expression | Recombinant |
| Purity | > 94% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: Sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | O88792 |
| NCBI Accession | NP_766235.1 |
| Background | Protein F11R |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Descripción
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F11R Antibody is a Rabbit Polyclonal antibody against F11R. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as a receptor for reovirus, a ligand for the integrin LFA1, involved in leukocyte transmigration, and a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
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