Mouse Insulin receptor substrate 4 (IRS4) ELISA Kit

Este producto es parte de IRS -Insulin receptor substrate
Mouse Insulin receptor substrate 4 (IRS4) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for IRS4

proveedor

Abbexa

reference

abx512484

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Insulin receptor substrate 4 (IRS4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Insulin receptor substrate 4 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Insulin receptor substrate 4 (IRS4) is another member of the IRS protein family, contributing to insulin and growth factor-mediated signal transduction. Unlike other IRS proteins, IRS4 displays a more tissue-specific expression pattern, being predominantly found in the brain, liver, and reproductive tissues. IRS4 is phosphorylated upon activation of insulin or insulin-like growth factor receptors, facilitating interactions with downstream signaling pathways, including PI3K and MAPK cascades. These pathways regulate diverse biological processes, such as energy metabolism, cell proliferation, and differentiation. IRS4 has garnered interest in the context of neurological development and metabolic regulation. Aberrant IRS4 expression or mutations have been linked to disorders like metabolic syndrome, infertility, and certain cancers. Understanding the unique role of IRS4 in signaling networks could provide insights into novel therapeutic strategies for metabolic and reproductive health challenges.

Características del producto

category

ELISA Kits


immunogen target

Insulin receptor substrate 4 (IRS4)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.078 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

IRS-4,160 kDa phosphotyrosine protein,CHNG9, PY160


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

IRS4


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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