Mouse Immunoglobulin Superfamily Member 8 (IGSF8) Protein
1235€ (100 µg)
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Name
Mouse Immunoglobulin Superfamily Member 8 (IGSF8) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx691440
Tested Applications
SDS-PAGE
Description
Mouse PGRL Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the mouse IGSF8 (AAH48387.1) (Met1-Thr577) was expressed with a C-terminal polyhistidine tag.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | PGRL |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Thr577 Tag: C-terminal His tag |
| Origin | Mouse |
| Observed MW | 60.2 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| NCBI Accession | AAH48387.1 |
| Alias | EWI2,PGRL,CD316,EWI-2,KCT-4,CD81P3,LIR-D1,Prostaglandin regulatory-like protein,CD81 partner 3,Glu-Trp-Ile EWI motif-containing protein 2 |
| Background | Protein IGSF8 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Background
IGSF8, also known as ECD8 or CD316, is expressed in a wide range of tissues, including immune cells, neuronal cells, and epithelial cells. It contains Ig-like domains and functions as a co-receptor involved in cell adhesion, cell signaling, and immune modulation. IGSF8 interacts with integrins and tetraspanins, playing a role in immune cell activation, antigen presentation, and synaptic organization. In the immune system, it facilitates interactions between antigen-presenting cells and T cells. Dysregulation of IGSF8 is linked to neurodegenerative diseases, such as Alzheimer’s disease, and its altered expression is observed in certain cancers, where it influences tumor-immune interactions and metastasis.
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