Immunoglobulin Superfamily Member 8 (IGSF8) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
IGSF8 Antibody is a Rabbit Polyclonal against IGSF8.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Immunoglobulin Superfamily Member 8 (IGSF8) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | BC053881 |
| Alias | EWI2,PGRL,CD316,EWI-2,KCT-4,CD81P3,LIR-D1,Prostaglandin regulatory-like protein,CD81 partner 3,Glu-Trp-Ile EWI motif-containing protein 2 |
| Background | Antibody anti-IGSF8 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
IGSF8, also known as ECD8 or CD316, is expressed in a wide range of tissues, including immune cells, neuronal cells, and epithelial cells. It contains Ig-like domains and functions as a co-receptor involved in cell adhesion, cell signaling, and immune modulation. IGSF8 interacts with integrins and tetraspanins, playing a role in immune cell activation, antigen presentation, and synaptic organization. In the immune system, it facilitates interactions between antigen-presenting cells and T cells. Dysregulation of IGSF8 is linked to neurodegenerative diseases, such as Alzheimer’s disease, and its altered expression is observed in certain cancers, where it influences tumor-immune interactions and metastasis.
Related Products
anti- IGSF8 antibody
May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.
Ver Producto
Immunoglobulin Superfamily Member 8 (IGSF8) Antibody
IGSF8 may play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.
Ver Producto
Immunoglobulin Superfamily Member 8 (IGSF8) Antibody
Immunoglobulin Superfamily, Member 8 Antibody is a Rabbit Polyclonal antibody against Immunoglobulin Superfamily, Member 8.
Ver Producto