Mouse Cis-Aconitate Decarboxylase (ACOD1) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ACOD1
proveedor
Abbexareference
abx528645Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Cis-Aconitate Decarboxylase (ACOD1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Cis-Aconitate Decarboxylase (ACOD1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Cis-aconitate decarboxylase (ACOD1), also known as immune-responsive gene 1 (IRG1), is an enzyme that converts cis-aconitate, an intermediate of the TCA cycle, into itaconate. Itaconate is a key immunometabolite with anti-inflammatory and antimicrobial properties, as it modulates cellular metabolism and inhibits the activity of pro-inflammatory enzymes like succinate dehydrogenase. ACOD1 is highly expressed in macrophages and other immune cells in response to inflammatory signals, such as lipopolysaccharide (LPS), playing a critical role in the metabolic reprogramming of immune responses. Dysregulation of ACOD1 has been implicated in inflammatory diseases and infections, with itaconate production acting as a protective mechanism against oxidative stress and pathogen growth. Its therapeutic potential is being investigated for modulating inflammation and treating immune-related disorders.
Características del producto
category
ELISA Kits
immunogen target
Cis-Aconitate Decarboxylase (ACOD1)
reactivity
Mouse
test range
78 pg/ml - 5000 pg/ml
sensitivity
< 36 pg/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
CAD,IRG1,Immune-responsive gene 1 protein
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ACOD1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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