Mouse Homeobox protein aristaless-like 3 (ALX3) ELISA Kit

Este producto es parte de ALX - ALX Homeobox
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Homeobox protein aristaless-like 3 (ALX3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501605
tested applications
ELISA

Description

Mouse Homeobox protein aristaless-like 3 (ALX3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Homeobox protein aristaless-like 3 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetHomeobox protein aristaless-like 3 (ALX3)
ReactivityMouse
Detection MethodColorimetric
Assay DataQuantitative
Test Range0.156 ng/ml - 10 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-15 working days. The validity for this kit is 6 months.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDO70137
Gene ID11694
AliasFND,FND1
BackgroundElisa kits for ALX3
StatusRUO
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ALX3 is a transcription factor belonging to the homeobox gene family, which regulates developmental processes, including craniofacial development, limb formation, and neural crest cell differentiation. ALX3 is expressed in facial mesenchymal tissues during embryogenesis, where it controls genes necessary for midline and upper facial development. Mutations or dysregulation of ALX3 are linked to frontonasal dysplasia, characterized by cleft lip/palate, hypertelorism, and nasal malformations. ALX3 has been shown to interact with other transcription factors and signaling pathways to regulate the proliferation and migration of mesenchymal cells. Emerging studies suggest ALX3 may act as a tumor suppressor in certain cancers, as its expression has been shown to inhibit cell proliferation and epithelial-mesenchymal transition (EMT). Its role in regulating gene expression during development and disease highlights ALX3 as a potential target for understanding congenital malformations and tumorigenesis.

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