Mouse Growth Differentiation Factor 15 (GDF15) Protein

Este producto es parte de GDF15 - Growth Differentiation Factor 15
Mouse Growth Differentiation Factor 15 (GDF15) Protein

Pida mas información

935106861

info@markelab.com

Precio

195€ (10 µg)

Protein GDF15

proveedor

Abbexa

reference

abx066941

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Mouse Growth Differentiation Factor 15 (GDF15) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).


Background

GDF15, a stress-responsive cytokine, stands as a distinct member within the diverse TGF-β superfamily. Its expression is typically low in most tissues during normal physiological conditions. However, when cardiac myocytes face ischemia or heightened ventricular wall stress, GDF-15 expression intensifies significantly. This cytokine has emerged as a potent prognostic indicator in various diseases, including heart diseases and cancer. Interestingly, it appears to act protectively against cardiac injury, attributed to its antihypertrophic, antiapoptotic, and anti-inflammatory properties, although the specific receptor through which GDF-15 exerts its effects remains unidentified. Studies have revealed a positive correlation between elevated GDF-15 levels and factors such as LV mass, IL-6, and MMP-9 levels in patients with heart failure (HF)

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E. coli


immunogen target

Growth Differentiation Factor 15 (GDF15)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 18.2 kDa Observed MW (SDS-PAGE): 20 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: His193-Val296 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

GDF15


dry ice

No


availability

Shipped within 5-7 working days.


alias

HG,PDF,MIC1;,PLAB,MIC-1,NAG-1,PTGFB, GDF-15


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


Quizá le pueda interesar

Human GDF15(Growth Differentiation Factor 15) ELISA Kit

Human GDF15(Growth Differentiation Factor 15) ELISA Kit

proveedor

FineTest

reference

EH0150

reactivity

human

status

RUO

Precio a consultar

Ver más

Mouse GDF15(Growth Differentiation Factor 15) ELISA Kit

Mouse GDF15(Growth Differentiation Factor 15) ELISA Kit

proveedor

FineTest

reference

EM0087

reactivity

mouse

status

RUO

Precio a consultar

Ver más

Rat GDF15(Growth Differentiation Factor 15) ELISA Kit

Rat GDF15(Growth Differentiation Factor 15) ELISA Kit

proveedor

FineTest

reference

ER0985

reactivity

rat

status

RUO

Precio a consultar

Ver más