Mouse G-protein coupled receptor 1 (GPR1) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse G-protein coupled receptor 1 (GPR1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx525976
tested applications
ELISA
Description
Mouse G-protein coupled receptor 1 (GPR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse G-protein coupled receptor 1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | G-protein coupled receptor 1 (GPR1) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8K087 |
| Gene ID | 241070 |
| Alias | GPR1,G protein-coupled receptor 1,chemerin chemokine-like receptor 2,GPR1,Chemerin2 |
| Background | Elisa kits for CMKLR2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
(CMKLR2), also known as GPR1, is a lesser-studied receptor within the chemerin signaling axis. CMKLR2 binds chemerin-derived peptides, though its affinity and downstream signaling pathways differ slightly from CMKLR1. CMKLR2 is expressed in neuronal tissues, endothelial cells, and adipocytes, suggesting diverse roles in metabolism and immune regulation. While its function remains under investigation, CMKLR2 is believed to modulate neuroinflammation and glucose homeostasis. In metabolic tissues, CMKLR2 influences insulin signaling and adipocyte differentiation, contributing to energy storage and utilization. In the central nervous system, CMKLR2 is implicated in regulating neural plasticity and inflammatory responses during neurodegenerative diseases like multiple sclerosis. Recent studies also highlight its role in tumor biology, where it may support angiogenesis and tumor progression under hypoxic conditions. The overlap of CMKLR2's signaling with CMKLR1 suggests a cooperative role in immune regulation, inflammation, and metabolic disorders. Targeting CMKLR2 alongside CMKLR1 could offer a broader therapeutic strategy for obesity, autoimmune conditions, and neurological disorders.
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