Mouse Free Fatty Acid Receptor 2 (FFAR2) Protein
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Mouse Free Fatty Acid Receptor 2 (FFAR2) Protein is a Recombinant Mouse protein expressed in E. coli.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Free Fatty Acid Receptor 2 (FFAR2) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 13.5 kDa Observed MW (SDS-PAGE): 16 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser241-Glu330 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl and 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | FFAR2,FFA2R,GPCR3,GPR43,G protein-coupled receptor 43 |
| Background | Protein FFAR2 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
FFAR2, also known as GPR43, is a G protein-coupled receptor that binds short-chain fatty acids (SCFAs) like acetate, propionate, and butyrate, which are produced by gut microbiota fermentation of dietary fiber. FFAR2 is expressed in immune cells, adipocytes, and the gastrointestinal tract, where it regulates energy metabolism, inflammation, and gut homeostasis. In immune cells, FFAR2 activation reduces inflammation by suppressing pro-inflammatory cytokine production and promoting anti-inflammatory responses, making it a critical modulator of immune function. In adipose tissue, FFAR2 signaling regulates lipolysis, adipogenesis, and energy expenditure, contributing to metabolic health. Dysregulation of FFAR2 has been implicated in obesity, inflammatory bowel disease (IBD), and metabolic disorders. It also plays a role in the gut-brain axis, influencing satiety and feeding behaviors. FFAR2 is a potential therapeutic target for inflammatory diseases, obesity, and metabolic dysfunction, as it links gut microbiota activity to host metabolism and immune regulation.
Related Products
Free Fatty Acid Receptor 2 (FFAR2) Antibody
Rabbit polyclonal antibody against FFAR2 protein. Immunogen region is C-terminal.
Ver Producto
Free Fatty Acid Receptor 2 (FFAR2) Antibody
This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for short chain free fatty acids and may be involved in the inflammatory response and in regulating lipid plasma levels.
Ver Producto
Mouse Free Fatty Acid Receptor 2 (FFAR2) ELISA Kit
Mouse Free Fatty Acid Receptor 2 (FFAR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Free Fatty Acid Receptor 2 (FFAR2) concentrations in tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Free Fatty Acid Receptor 2 (FFAR2)
Ver Producto