Mouse Free Fatty Acid Receptor 2 (FFAR2) ELISA Kit

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Description
Mouse Free Fatty Acid Receptor 2 (FFAR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Free Fatty Acid Receptor 2 (FFAR2) concentrations in tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Free Fatty Acid Receptor 2 (FFAR2)
Documents del producto
Product specifications
Category | ELISA Kits |
Immunogen Target | Free Fatty Acid Receptor 2 (FFAR2) |
Reactivity | Mouse |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Assay Type | Sandwich |
Test Range | 0.156 ng/ml - 10 ng/ml |
Sensitivity | < 0.06 ng/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Size 2 | 5 × 96 tests |
Size 3 | 10 × 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
Alias | FFAR2,FFA2R,GPCR3,GPR43,G protein-coupled receptor 43 |
Background | Elisa kits for FFAR2 |
Status | RUO |
Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
FFAR2, also known as GPR43, is a G protein-coupled receptor that binds short-chain fatty acids (SCFAs) like acetate, propionate, and butyrate, which are produced by gut microbiota fermentation of dietary fiber. FFAR2 is expressed in immune cells, adipocytes, and the gastrointestinal tract, where it regulates energy metabolism, inflammation, and gut homeostasis. In immune cells, FFAR2 activation reduces inflammation by suppressing pro-inflammatory cytokine production and promoting anti-inflammatory responses, making it a critical modulator of immune function. In adipose tissue, FFAR2 signaling regulates lipolysis, adipogenesis, and energy expenditure, contributing to metabolic health. Dysregulation of FFAR2 has been implicated in obesity, inflammatory bowel disease (IBD), and metabolic disorders. It also plays a role in the gut-brain axis, influencing satiety and feeding behaviors. FFAR2 is a potential therapeutic target for inflammatory diseases, obesity, and metabolic dysfunction, as it links gut microbiota activity to host metabolism and immune regulation.
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