Mouse Follistatin Like Protein 3 (FSTL3) Protein
234€ (10 µg)
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935106861
info@markelab.com
name
Mouse Follistatin Like Protein 3 (FSTL3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167858
tested applications
WB, SDS-PAGE
Description
Follistatin Like Protein 3 is a recombinant Mouse protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Follistatin Like Protein 3 (FSTL3) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 28.6 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Val24-Val256 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | FLRG,FSRP,Follistatin-related gene protein,Follistatin-like protein 3,Follistatin-related protein 3 |
| Background | Protein FSTL3 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Follistatin Like 3 (FSTL3) is a glycoprotein structurally related to follistatin and functions as an extracellular antagonist of activin and other TGF-β superfamily members. By binding to activin, FSTL3 inhibits its signaling, thereby regulating processes such as cell differentiation, growth, and immune responses. FSTL3 is expressed in various tissues, including the heart, pancreas, and reproductive organs, where it plays roles in modulating endocrine functions, metabolic homeostasis, and tissue repair. Elevated levels of FSTL3 have been associated with metabolic disorders like obesity and type 2 diabetes, where it disrupts insulin signaling and glucose metabolism. Additionally, FSTL3 is implicated in cancer progression, fibrosis, and cardiovascular diseases, due to its influence on cell proliferation and extracellular matrix remodeling. Its multifunctional regulatory properties make FSTL3 a potential therapeutic target for treating activin-related pathologies, including metabolic syndrome, infertility, and fibrotic diseases.
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