Follistatin Like Protein 3 (FSTL3) Antibody
286€ (100 µl)
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935106861
info@markelab.com
name
Follistatin Like Protein 3 (FSTL3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx129885
tested applications
WB, IHC, IF/ICC
Description
Follistatin Like Protein 3 Antibody is a Rabbit Polyclonal against Follistatin Like Protein 3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Follistatin Like Protein 3 (FSTL3) |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9EQC7 |
| Alias | FLRG,FSRP,Follistatin-related gene protein,Follistatin-like protein 3,Follistatin-related protein 3 |
| Background | Antibody anti-FSTL3 |
| Status | RUO |
Descripción
Follistatin Like 3 (FSTL3) is a glycoprotein structurally related to follistatin and functions as an extracellular antagonist of activin and other TGF-β superfamily members. By binding to activin, FSTL3 inhibits its signaling, thereby regulating processes such as cell differentiation, growth, and immune responses. FSTL3 is expressed in various tissues, including the heart, pancreas, and reproductive organs, where it plays roles in modulating endocrine functions, metabolic homeostasis, and tissue repair. Elevated levels of FSTL3 have been associated with metabolic disorders like obesity and type 2 diabetes, where it disrupts insulin signaling and glucose metabolism. Additionally, FSTL3 is implicated in cancer progression, fibrosis, and cardiovascular diseases, due to its influence on cell proliferation and extracellular matrix remodeling. Its multifunctional regulatory properties make FSTL3 a potential therapeutic target for treating activin-related pathologies, including metabolic syndrome, infertility, and fibrotic diseases.
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