Mouse Fc Receptor-Like Protein 1 (FCRL1) Protein
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Description
Mouse Fc receptor-like Protein is a recombinant protein from Mouse produced in Human Cells. Recombinant Mouse Fc receptor-like protein 1 is produced by our Mammalian expression system and the target gene encoding Ala17-Ser219 is expressed with a 6His tag at the C-terminus.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Fc receptor-like |
| Host | Human |
| Origin | Mouse |
| Observed MW | Molecular Weight: 22.5 kDa Sequence Fragment: Ala17-Ser219 Tag: C-terminal 6 His tag |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | PBS, pH7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Store at < -20°C. |
| Dry Ice | No |
| UniProt ID | Q8R4Y0 |
| Alias | Fc receptor-like protein 1FcR-like protein 1,FcRL1,Fc receptor homolog 1,FCRH1,IFGP1,IRTA5,CD307a |
| Background | Protein FCRL1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Fc Receptor Like 1 (FCRL1) is a transmembrane protein expressed primarily on B cells and is a member of the immunoglobulin superfamily. It plays a role in regulating B cell activation and immune responses. The cytoplasmic domain of FCRL1 contains both immunoreceptor tyrosine-based activation motifs (ITAMs) and immunoreceptor tyrosine-based inhibitory motifs (ITIMs), suggesting it can transmit both activating and inhibitory signals. Dysregulation of FCRL1 expression has been associated with autoimmune conditions like systemic lupus erythematosus (SLE), indicating its importance in immune tolerance and balance.
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