Fc Receptor-Like Protein 1 (FCRL1) Antibody
292.5€ (80 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Fc Receptor-Like Protein 1 (FCRL1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx030308
Tested Applications
ELISA, WB
Description
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Fc Receptor-Like Protein 1 (FCRL1) Immunogen: KLH-conjugated synthetic peptide between 366-392 amino acids from the C-terminal region of human FCRL1. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 46.9 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96LA6 |
| Alias | Fc receptor-like protein 1FcR-like protein 1,FcRL1,Fc receptor homolog 1,FCRH1,IFGP1,IRTA5,CD307a |
| Background | Antibody anti-FCRL1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Fc Receptor Like 1 (FCRL1) is a transmembrane protein expressed primarily on B cells and is a member of the immunoglobulin superfamily. It plays a role in regulating B cell activation and immune responses. The cytoplasmic domain of FCRL1 contains both immunoreceptor tyrosine-based activation motifs (ITAMs) and immunoreceptor tyrosine-based inhibitory motifs (ITIMs), suggesting it can transmit both activating and inhibitory signals. Dysregulation of FCRL1 expression has been associated with autoimmune conditions like systemic lupus erythematosus (SLE), indicating its importance in immune tolerance and balance.
Productos relacionados
Fc Receptor-Like Protein 1 (FCRL1) Antibody
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoprotei…
Ver producto
Fc receptor-like protein 1 (FCRL1) Antibody
Fc receptor-like protein 1 (FCRL1) Antibody is a mouse monoclonal antibody against Fc receptor-like protein 1 (FCRL1).…
Ver producto Fc receptor-like protein 1 (FCRL1) Antibody (PE)
Fc receptor-like protein 1 (FCRL1) Antibody (PE) is a PE-conjugated Mouse Monoclonal antibody for Fc receptor-like prote…
Ver producto